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MLB DFS Picks: Three must-start fantasy baseball players for Friday 3/28/25

MLB DFS Picks: Three must-start fantasy baseball players for Friday 3/28/25

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By: Garion Thorne

As per usual, we’re left with a slightly smaller set of games for Day 2 of the MLB regular season. For the purposes of this article, we’ll be focusing on tonight’s eight-game featured slate on DraftKings. Apologies to the Rays and Rockies.

Allow me to dive in and highlight three must-start assets on Friday evening.

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SP Yoshinobu Yamamoto, Los Angeles Dodgers vs. Detroit Tigers, $9,000

With each and every new data point, it appears that Yamamoto is one of the best pitchers in baseball. If you remove his one-inning MLB debut in Korea, Yamamoto has dazzled in his time with the Dodgers, pitching to a 2.49 ERA and a 2.55 FIP across 94.0 innings of work. That also includes a 28.3% strikeout rate and a 4.9 K/BB ratio. It truly feels like raw volume is the lone thing keeping his price point at $9,000 this evening, though as someone who has already thrown five innings in a non-exhibition setting in 2025, ironically, volume is less of a concern for Yamamoto than most starters this time of the year.

Matchup isn’t really a concern, either. While the Tigers have a couple new pieces in their lineup this season, this roster still very much resembles the one that ranked 23rd in wRC+ (95) and eighth in strikeout rate (24.3%) in 2024. Yamamoto barely broke a sweat in Japan against the Cubs. I’m envisioning a similar script on Friday.


1B Vladimir Guerrero Jr., Toronto Blue Jays vs. Baltimore Orioles, $5,300

I think this game has the potential to be very high scoring, and if the Jays are going to bounce back after a brutal Opening Day, it’ll likely be an effort led by their Silver Slugger first baseman. Guerrero was quiet during Thursday’s loss — as was most of Toronto’s lineup — but you don’t have to look back too far to see how dangerous the All-Star can be. From May 1 on in 2024, Guerrero slashed .345/.412/.590 with a .245 ISO and a 181 wRC+ across 561 plate appearances. Tonight, he’ll face off with Charlie Morton ($7,000), who is now 41-years-old and is starting to see the impacts of that age on his performance. Morton pitched to a 4.49 xERA in 2024 and surrendered a whopping 1.56 home runs per nine to right-handed opponents. Vlad could be looking at his first long ball of 2025 in a few hours time.


OF Kyle Stowers, Miami Marlins vs. Pittsburgh Pirates, $2,400

I’ll be honest, I wasn’t expecting to advocate for a Marlin this early into the season. Still, for as underwhelming as this roster appears to be, someone has to hit in the top-third of this lineup that isn’t named Xavier Edwards ($4,000). On Thursday, Stowers was one of those people, finishing his day batting out of the two-spot with a pair of walks, a single, an RBI and a run scored. Aside from an ideal spot in the order and a microscopic price tag, Stowers has a platoon advantage working in his favor this evening. Mitch Keller ($7,900) struggled a lot down the stretch in 2024 — specifically with left-handed bats. In his final 10 starts, Keller allowed lefties to combine for 2.31 home runs per nine and a robust .422 wOBA. Yikes.

Garion is a Toronto-based writer who has been playing fantasy sports since elementary school. With a particular affinity for advanced statistics and sabermetrics, he’s been covering DFS Baseball, Football and Basketball for DraftKings dating back to 2018. Prior to that, Garion’s work could be found at FNTSY, SportsGrid, HoopsHype, The New York Daily News and Sportsnet.ca. Still, he is a Dolphins fan, so his decision-making can be questioned from time-to-time.
Disclaimer

All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.