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NBA Best Bets: Top James Harden player props for Clippers vs. Grizzlies on 3/21/25

NBA Best Bets: Top James Harden player props for Clippers vs. Grizzlies on 3/21/25

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By: Keagan Smith

At 10:30 p.m. EST tonight, the Los Angeles Clippers host the Memphis Grizzlies to round out the NBA’s late slate. L.A. All-Star James Harden is playing great ball at the moment, and he looks to lead his team to a key win against a Western Conference foe.

Here’s the top Harden prop bet on DraftKings Sportsbook for tonight’s action.

Best James Harden prop bets on DraftKings Sportsbook

Harden’s prop lines on DraftKings Sportsbook are set at 22.5 points, 5.5 rebounds, 8.5 assists, and 3.5 three-pointers. His combined PTS + REB + AST line is currently 37.5.

This game carries a total of 229.5 points on DKSB and the Clippers are currently -285 Moneyline favorites. The Grizzlies’ defense ranks just outside the top-10 in DRTG while the team plays at the league’s fastest pace. However, they’re actually 25th in opponent points allowed per game, so the potential for a high-scoring shootout is real.

The first Harden prop to check out is over 14.5 AST + REB. The 35-year-old guard is still a contributor across multiple stat categories and averages 5.9 rebounds with 8.7 assists per contest. His AST + REB lines have been a sneaky-good pick through most of the season with a 37/66 hit rate, including five of his last six appearances. At -120 odds, this is a reliable prop to take a look at as a starter piece on your betting card.

Over 22.5 points for Harden is another prop bet to check out as the Clippers take on the Grizzlies tonight. He’s excelled at putting the ball through the hoop as of late and went over this line in seven consecutive games before falling just short with 22 points in his last contest. With an average of 26.7 points over his last 10 appearances, ride his hot streak while you can at -115 odds.

Keagan is a Texas-based editor and analyst who believes sports are the true eighth wonder of the world. After starting out in local media, he’s provided coverage for DraftKings Network since 2024. He gravitates toward football, hoops and hockey, but is happy to watch and write about any game that involves a ball or a puck. While his own athletic career ended in middle school, he’s also an avid fantasy player with a soft spot for dynasty formats, spending countless hours crafting the ever-elusive perfect squad.
Disclaimer

I am a promoter at DraftKings and am also an avid fan and user and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skills and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.