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After a long and wildly entertaining offseason, the NFL is finally back in action with a great Week 1 lineup to get the regular season underway. There are six divisional games as part of the Sunday afternoon action before two more divisional rivalries take center stage in the primetime matchups.
Each week to help you find the stats and trends that matter, I’ll be posting the relevant info for every matchup from DraftKings Sportsbook. You can use these numbers to fill out your Week 1 betting card or to build an awesome Parlay play.
All odds provided by DraftKings Sportsbook and all odds subject to change.
Detroit Lions at Kansas City Chiefs
Relevant Records
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Betting Trends
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The NFL regular season kicks off with the defending Super Bowl champions hosting the Lions, who are expected to continue their turnaround under coach Dan Campbell. The Chiefs went 17-3 SU on their title run last season but only 8-11-1 ATS. The Lions had the opposite trend going 12-5 ATS but only 9-8 SU. These teams will be meeting for the first time since 2019, when the Chiefs won SU but the Lions covered ATS in a high-scoring, 34-30 Chiefs’ win in Detroit. Since coach Andy Reid arrived in Kansas City in 2023, the Chiefs are 9-1 SU and 7-3 ATS in their 10 Week 1 matchups.
San Francisco 49ers at Pittsburgh Steelers
Relevant Records
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Betting Trends
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Tampa Bay Buccaneers at Minnesota Vikings
Relevant Records
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Betting Trends
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Tennessee Titans at New Orleans Saints
Relevant Records
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Betting Trends
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Houston Texans at Baltimore Ravens
Relevant Records
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Betting Trends
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Jacksonville Jaguars at Indianapolis Colts
Relevant Records
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Betting Trends
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These two AFC South rivals start off the season with a matchup at Lucas Oil Stadium in one of the eight games that start in the early window. This will be the start of a new era for the Colts with first-year head coach Shane Steichen at the helm and rookie QB Anthony Richardson under center. Last season, the Jaguars beat the Colts SU/ATS 24-0 in Jacksonville in Week 2, but the Colts got a 34-27 SU/ATS win at home in Week 6. The home team has won each of the last 11 head-to-head matchups between these two teams.
Cincinnati Bengals at Cleveland Browns
Relevant Records
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Betting Trends
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Arizona Cardinals at Washington Commanders
Relevant Records
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Betting Trends
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Carolina Panthers at Atlanta Falcons
Relevant Records
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Betting Trends
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Miami Dolphins at Los Angeles Chargers
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Betting Trends
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Philadelphia Eagles at New England Patriots
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Betting Trends
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The Eagles will be looking to avoid the “Super Bowl hangover” as they open their season with a road trip to New England. The Eagles were 7-0 SU last year as road favorites but only 2-5 ATS, while the Patriots were 0-3 ST/ATS as home underdogs without ever covering. Since the 1969 season, Super Bowl losers have gone 23-31 ATS and 28-26 SU in Week 1 of the following season, and in the last 23 years, the teams that lost the Super Bowl are just 4-19 ATS and 9-14 SU the following Week 1. The Patriots have only hit the 1H Moneyline in 5 of their last 20 games, but they have hit the Team Total Over in 13 of those 20 games.
Green Bay Packers at Chicago Bears
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Betting Trends
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Los Angeles Rams at Seattle Seahawks
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Betting Trends
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Las Vegas Raiders at Denver Broncos
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Betting Trends
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Dallas Cowboys at New York Giants
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Betting Trends
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The Giants host the Cowboys for Sunday Night Football in an NFC East showdown. The Cowboys have gone 11-1 SU/9-3 ATS in their last 12 head-to-head matchups, and the over is 7-2 in their last nine meetings. Dallas has hit its team over in 14 of its last 22 contests, and New York has hit its team over in 15 of its last 22 contests.
Buffalo Bills at New York Jets
Relevant Records
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Betting Trends
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Week 1 wraps up with a great matchup between the Jets and Bills, and all eyes will be on Aaron Rodgers in his debut for the Jets. The two teams split their head-to-head matchups last year with each team winning at home. The Jets won 20-17 in Week 9 but lost 20-12 in Week 14. Since this will be primarily a showcase of the two QBs, here are some quick numbers on Rodgers and Josh Allen: Rodgers is 6-1 ATS in his career as a starter in the regular season when a home underdog, Rodgers is 10-5 SU/8-7 ATS as a starter in Week 1, Rodgers is 12-6 SU/10-8 ATS as a starter on Monday Night Football, Allen is 40-11 SU/28-21-2 ATS as a regular season favorite, Allen is 3-3 SU/ATS as a starter on Monday Night Football, and Allen is 3-1 SU/ATS as a starter in Week 1.
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I am a promoter at DraftKings and am also an avid fan and user (my username is z.thompson) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and do not constitute a representation that any particular strategy will guarantee success. All customers should use their own skill and judgment in building lineups. I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.