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Fantasy Baseball Rankings: DraftKings MLB DFS Picks for April 21

Matt Meiselman ranks the top fantasy baseball plays in each salary range for Wednesday’s main DraftKings MLB slate.

Cincinnati Reds v San Francisco Giants Photo by Ezra Shaw/Getty Images

Wednesday’s main DraftKings MLB slate has a start time of 6:10 p.m. ET. For up-to-the-minute news related to today’s DraftKings MLB slate, download the DK Live app and follow DK Live on Twitter at @dklive.

The idea of this fantasy baseball rankings page is to rank the top DraftKings options in each salary range, helping you make quick decisions when debating which players to roster for the upcoming main DraftKings MLB slate.

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Notable Lineup Absences

Team Name Position Injury Status
Team Name Position Injury Status
Atlanta Braves Ronald Acuna RF Ehire Adrianza will continue to start in RF with Acuna out.
Cincinnati Reds Nicholas Castellanos RF Tyler Naquin will shift into RF with Castellanos suspended.

DraftKings Sportsbook Betting Odds

Teams Moneyline Total Runs
Teams Moneyline Total Runs
SF Giants +108 Over 8
PHI Phillies -127 Under 8
BAL Orioles +138 Over 7.5
MIA Marlins -165 Under 7.5
HOU Astros -155 Over 10
COL Rockies +132 Under 10
MIN Twins -106 Over 8
OAK Athletics -110 Under 8
STL Cardinals +148 Over 8
WAS Nationals -175 Under 8
TEX Rangers +155 Over 8.5
LA Angels -182 Under 8.5
MIL Brewers +175 Over 7.5
SD Padres -210 Under 7.5
ATL Braves +105 Over 9
NY Yankees -122 Under 9
ARI Diamondbacks +155 Over 8
CIN Reds -182 Under 8
TOR Blue Jays +102 Over 10
BOS Red Sox -118 Under 10
NY Mets -137 Over 7
CHI Cubs +118 Under 7



Player Name Position Opp Salary
Player Name Position Opp Salary
Tyler Mahle SP ARI $9,500
David Peterson SP CHC $7,100
Jakob Junis SP TB $6,400
Michael Fulmer SP PIT $5,700


Studs ($5,000+)

Player Name Position Opp Salary
Player Name Position Opp Salary
J.D. Martinez OF TOR $6,100
Freddie Freeman 1B NYY $5,900
Bo Bichette SS BOS $5,800
Vladimir Guerrero Jr. 1B BOS $5,700
Aaron Judge OF ATL $5,300
Marcus Semien 2B BOS $5,200

Midrange ($4,000-$4,900)

Player Name Position Opp Salary
Player Name Position Opp Salary
Pete Alonso 1B CHC $4,900
Marcell Ozuna OF NYY $4,800
Jesse Winker OF ARI $4,500
Giancarlo Stanton OF ATL $4,400
Gary Sanchez C ATL $4,300
Austin Meadows OF KC $4,100
Alex Verdugo OF TOR $4,100
Randal Grichuk OF BOS $4,000

Salary Relief ($3,900 and under)

Player Name Position Opp Salary
Player Name Position Opp Salary
Cavan Biggio 3B BOS $3,900
Kike Hernandez OF TOR $3,900
Brandon Nimmo OF CHC $3,600
Nick Senzel OF ARI $3,500
Bobby Dalbec 1B TOR $3,500
Michael Conforto OF CHC $3,400
Andrew Benintendi OF TB $3,100
Rowdy Tellez 1B BOS $3,000

Offense Notes

High Ownership on AL East Teams

The field’s top choices for Wednesday night’s slate all look to be coming from the AL East, with the Yankees still underpriced, the Jays and Red Sox facing two of each other’s weakest starting pitchers, and the Rays having several left-handed value plays that make them an affordable stack. Toronto is by far the most expensive of these teams, and it’s hard to tell how their ownership will compare to the other more affordable teams. It’s an unusual pitching slate as well with no true aces on the mound, and it could be a common strategy for many people to simply punt at pitcher and pay up for some of these expensive stacks. All four are probably good choices, but they could all be over-owned as well. Of this group, the Rays may be the most appealing if for no other reason than the fact they will likely be facing a highly owned pitcher in Jakob Junis ($6,400). Junis could be the most popular SP2 on this slate, and it’s a slate where cheap pitchers will be highly owned in general, so that could keep the Tampa ownership in check and also give them a decent amount of leverage.

Set your DraftKings fantasy baseball lineups here: MLB $150K Bat Flip [$50K to 1st]

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All views expressed are my own. I am an employee of DraftKings and am ineligible to play in public DFS or DKSB contests.

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