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NFL 2021 Week 5 DraftKings Picks: Fantasy Football Start, Sit, Sleepers

Pat Mayo goes position-by-position breaking down the Sunday NFL slate, giving his Week 5 DraftKings picks for GPPs.

Pat Mayo and Peter Overzet go position-by-position, providing their Week 5 DraftKings picks for the NFL Sunday main slate.

Set your DraftKings fantasy football lineups here: NFL $4M Fantasy Football Millionaire [$1M to 1st + ToC Entry]

Week 5 Game-by-Game Previews

Week 5 — Best Bets | Game Picks | DraftKings Picks | Optimizer

Week 5 — Rankings | RB | WR | TE | QB | DST | Projections

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How to Use DK Tools — Optimizer | Game Sims | Player vs Player Compare

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2021 NFL Week 5 DraftKings Picks Tournament Plays (GPPs)

Player Projections | Advanced Stats | How to Use DraftKings Tools

Tournament plays are more volatile players (boom or bust) who can help differentiate your lineup in giant GPPs. Mixing a few of these names, along with the safer cash-game options, is a great way to construct a GPP roster.


Kyler Murray $8,000
Kirk Cousins $6,500
Joe Burrow $6,100

How to Use DK Tools — Optimizer | Game Sims | Player vs Player Compare


Derrick Henry $9,000
Ezekiel Elliott $7,000
James Robinson $6,000
Damien Harris $5,500
Samaje Perine $4,000

How To Bet on NFL — Guide + Strategy | Podcast | For Beginners | Gambling Myths


Davante Adams $8,200
Justin Jefferson $7,700
Ja’Marr Chase $5,800
Laviska Shenault $4,800
Kadarius Toney $4,000


TJ Hockenson $5,500
Ricky Seals-Jones $2,500


Patriots $4,900
Cowboys $2,800
Jaguars $2,100

NOTE: Picks for Sunday’s main slate only

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Pat Mayo is an award-winning video host and producer of long and short-form content, and the host of The Pat Mayo Experience daily talk show. (Subscribe for video or audio). Mayo (@ThePME) won the 2020 Fantasy Sports Writing Association Daily Fantasy Writer of the Year and Golf Writer of the Year awards, along with the Fantasy Sports Trade Association Best Sports Betting Analyst award, and was a finalist for four FSWA Awards in 2020 (Best Podcast, Best Video, Daily Fantasy Writer of the Year, Golf Writer of the Year). His 21 FSWA nominations lead all writers this decade and are third-most all-time. Mayo has been recognized across multiple sports (Football, Baseball & Golf), mediums (Video, Writing & Podcasting), genre (Humor), and game formats (Daily Fantasy and Traditions Season Long). Beyond sports, Mayo covers everything from entertainment to pop culture to politics. If you have a fantasy question, general inquiry or snarky comment, ship it to Mayo at and the best will be addressed on the show.

I am a promoter at DraftKings and am also an avid fan and user (my username is ThePME) and may sometimes play on my personal account in the games that I offer advice on. Although I have expressed my personal view on the games and strategies above, they do not necessarily reflect the view(s) of DraftKings and I may also deploy different players and strategies than what I recommend above. I am not an employee of DraftKings and do not have access to any non-public information.

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