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DraftKings Fantasy Football Early Look: NFL Week 12 DFS Picks, Sleepers, Fades

Julian Edlow goes position-by-position breaking down some of the best and worst NFL targets for Week 12’s main DraftKings fantasy football slate, which locks at 1:00 p.m. ET on November 29.

Even with a three-game appetizer this week on Thanksgiving, we still get a full 11-game main fantasy football slate on Sunday to enjoy. Here’s what jumps out in my first look at the Week 12 NFL slate on DraftKings.

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Josh Allen, Buffalo Bills vs. Los Angeles Chargers ($7,600) — This one should be a shootout, with Allen and Justin Herbert ($7,200) both making for very safe and popular plays, also bringing a lot of upside into this matchup. Allen comes out of the bye after getting back on the pace he had earlier in the season, scoring 39 DKFP against Seattle and 29 DKFP against Arizona. The Chargers rank 28th in DKFP allowed to QB, and the matchup is just as good on the other side for Herbert, with Buffalo ranked 31st. Lots of throwing, lots of points.

Cam Newton, New England Patriots vs. Arizona Cardinals ($6,400) — Allen and Herbert are the two QBs to focus on, but Newton is in a spot to consider. The way the Patriots want to win seems to be running the ball and asking Cam to do less — like his 17 passing attempt game in Week 10 versus Baltimore. Last week should’ve been the same script, but we saw Newton air it out 40 times in just a one possession game. If there’s a chance he does that against versus Arizona, which ranks 30th in DKFP allowed to QB, I’d have some interest at low ownership.


Matt Ryan, Atlanta Falcons vs. Las Vegas Raiders ($5,900) — After a dud against New Orleans, we catch Ryan in a great bounce-back spot. Matty Ice is the cheapest he’s been all season, and sets up as a home underdog against a Vegas defense that ranks 23rd in DKFP allowed to QB. Averaging almost 39 passing attempts per game, we can count on volume here in a great matchup.

Other Options: Derek Carr ($5,700), Daniel Jones ($5,500), Baker Mayfield ($5,300)

Running Back


Dalvin Cook, Minnesota Vikings vs. Carolina Panthers ($9,500) — Jamming this salary in can get complicated, but Cook’s proven to be matchup-proof, averaging 28.7 DKFP. In four games back from injury, he’s seen 30-plus touches three times. Now Cook is a home favorite on DraftKings Sportsbook against one of the league’s worst rush defenses, ranking 30th in DKFP allowed. This is as strong of a spot as you could ask for a running back to be in.

Josh Jacobs, Las Vegas Raiders at Atlanta Falcons ($7,200) — It’s a strange week with some of the top RB plays off the main slate, and Alvin Kamara ($8,200) in a far different role with Drew Brees (ribs) out — zero receptions last week in a prime matchup against Atlanta. It’s not a week to pay up for two backs, I’d rather go big on Cook and look for a cheap RB to pair him with. However, if you want to be different, we should be able to trust Jacobs for a large role in a good matchup. Like we covered, the Raiders are favorites here, and the Falcons rank 24th in DKFP allowed to RB. Vegas isn’t afraid to feed Jacobs a massive workload in the right spots.


Wayne Gallman, New York Giants at Cincinnati Bengals ($5,000)

The Giants come out of the bye as sizable road favorites on DraftKings Sportsbook over the Bengals, a lot of which has to do with Joe Burrow’s knee injury. That leaves Gallman in a solid spot against a middle of the pack Cincy run defense. Gallman’s piled up at least 13 touches in each of the last four games, a span in which he’s averaging 15.8 DKFP, thanks to five trips to the end zone. I’ll continue to trust him in this spot at a discount.

Other Options: Kalen Ballage ($5,800), Nyheim Hines ($4,600), Salvon Ahmed ($5,100)

Wide Receiver


Keenan Allen, Los Angeles Chargers at Buffalo Bills ($8,000) — Allen might finally be hitting that price point where we need to fade him, but given the matchup, we have to mention him. This should be a barn burner in Buffalo, and Allen’s been an absolute target monster with Herbert at the helm. Last week against the Jets was the second time Keenan’s seen 19 targets in a game, and it translated to a 16-145-1 line (38.5 DKFP) — his fourth consecutive game with a touchdown. The only reason to fade is being priced at his most expensive point of the season by $600, sitting at $6,200 when the hot streak began.

Tyreek Hill, Kansas City Chiefs at Tampa Bay Buccaneers ($7,800) — The Bucs may have a good defense at times, but Tampa ranks just 23rd in DKFP allowed to WR, and we’ve seen it get burned too much to shy away from the matchup — especially when the Chiefs’ offense is on the other side. After a couple of quiet weeks, Hill’s been picking up steam, and this is a matchup we should see momentum continue. Hill has six touchdowns in his last four games, has scored at least 25 DKFP in his last three games, and is coming off back-to-back games with 100 yards and at least one touchdown. In those last two games against Carolina and Vegas, Hill’s averaging 33 DKFP on 16 targets per game.


Michael Pittman Jr., Indianapolis Colts vs. Tennessee Titans ($5,000) — In a season that’s seen T.Y. Hilton ($3,900) essentially disappear, we might be seeing a rookie emerge as Indy’s WR1 of the future. Pittman’s had his three best games of his career the last three weeks, with his best coming in this matchup on TNF in Week 10. Pittman caught 7-of-8 targets for 101 yards against the Titans, along with a carry for 21 yards (22.2 DKFP). He followed that up last week with a 3-66-1 line (15.6 DKFP) against the Packers, scoring his first career touchdown. Expect him to remain heavily involved moving forward.

Other Options: Justin Jefferson ($6,300), Antonio Brown ($5,700), Jakobi Meyers ($5,300), Damiere Byrd ($4,100)

Tight End


Darren Waller, Las Vegas Raiders at Atlanta Falcons ($6,000) — We almost have to spend at TE this week due to the lack of value. As someone that prefers to punt at TE, I’m hoping some news sparks value by Sunday. But for now, there are a few directions to go in. I chose Waller here because he’s $1,000 cheaper than Travis Kelce ($7,000) and has the better matchup. That said, Kelce’s seen double-digit targets in three straight, and is averaging 29 DKFP in those games. He’s the top overall TE play, followed by Waller. Hunter Henry ($4,800) is another mid-range consideration in a great matchup against Buffalo.


Trey Burton, Indianapolis Colts vs. Tennessee Titans ($3,200) — If you make me punt here, I’ll take Burton. He’s been consistently involved for the Colts, and even gets some looks in the run game in the red zone. The Titans also rank 27th in DKFP allowed to TE.



New Orleans Saints DST ($3,800) at Denver BroncosI’m not in love with paying this much for a defense on the road, but we can at least make the case. The Broncos got the upset at home over the Dolphins last week, but it wasn’t thanks to their offense. This team really struggles to move the ball, and New Orleans has been spectacular on the defensive side over the last few weeks. The Saints’ DST scored 16 DKFP against the Bucs, 14 against the Niners and 16 against the Falcons the last three games, and none of those points came from any fluke touchdowns. New Orleans has allowed just 25 total points in those games, with 13 sacks and nine turnovers.


Denver Broncos DST ($2,200) vs. New Orleans Saints — On the flip side of the matchup, the Broncos are still a strong defense, and the Saints are a completely different offense with Taysom Hill ($6,200). The Falcons managed 5.0 DKFP in this matchup last week, and the Broncos’ DST is coming off 12 DKFP versus Miami last week.

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