The Lions have the No. 1 scoring offense in the NFL through four weeks but also have some big injury issues. D’Andre Swift is out, while Amon-ra St. Brown is banged up. Detroit’s defense has also been shredded, which has resulted in some high-scoring losses.
The Patriots are down their starting and backup quarterback, which means Bailey Zappe is in line for the start after appearing in Week 4 against the Packers. New England’s defense has been solid, but this will be its toughest test of the season.
The Patriots are 3-point favorites per DraftKings Sportsbook. The total is set at 45.5.