When the Seattle Seahawks host the San Francisco 49ers on Sunday, it’s a matchup between a first- and last-place teams. That doesn’t mean much in the NFC West, the best division in football. The Niners (4-3) have won two straight to pull above .500. Most recently, they destroyed the Patriots in Foxborough, 33-6. San Francisco is 3-0 on the road this year.
Something will have to give Sunday, though, as the Seahawks (5-1) are unbeaten at home. Their lone loss came in Arizona this past week. Even then, they took the Cardinals to overtime. Russell Wilson is probably the MVP frontrunner right now, leading the NFL by a wide margin with a 119.3 QB rating. Still, the Seahawks don’t have much margin for error with three teams on their heels for the division lead.
Here’s how to watch Sunday’s game, odds for the matchup, key injuries, and notable fantasy football start/sit considerations.
Date: Sunday, Nov. 1
Time: 4:25 p.m. ET
Notable Statistical rankings (Football Outsiders)
Fantasy football start/sit advice
JaMycal Hasty, RB, $5,000
The 49ers are a running back factory and Hasty could be their next great specimen. The rookie looked explosive Sunday, rushing for 57 yards on just nine carries and catching a 16-yard pass. With Tevin Coleman, Raheem Mostert and now Jeff Wilson Jr. banged up, Hasty could be in line to be the Niners’ featured back against Seattle.
Brandon Aiyuk, WR, $5,800
WR1 Deebo Samuel is likely to miss some time with a hamstring injury, making Aiyuk the new No. 1 in San Francisco. That’s awesome news considering the Seahawks have allowed more fantasy points to wide receivers than any other team.
Carlos Hyde, RB, $5,300
Chris Carson suffered a foot injury against the Cardinals, paving the way for Hyde to take on a bigger role. He made the most of it, with 15 carries for 68 yards and a TD. If Carson cannot play this Sunday, Hyde is worth a look. However, keep in mind that the Niners are top-10 against the run.
Tyler Lockett, WR, $7,100
Lockett is coming off one of the best games you’ll ever see from a receiver, racking up 200 yards and three touchdowns against the Cardinals. While we can’t expect him to replicate that, it’s a great sign that he seems to hitting his stride after battling a leg injury early in the season. That said, the Niners are top-5 against the pass and in two games against them last year, Lockett only had 77 yards and a touchdown.