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Saquon Barkley injury: What status means for Week 6

Saquon Barkley is dealing with an ankle injury for Week 6. We break down what it means for betting and DFS decisions.

Saquon Barkley #26 of the New York Giants runs with the ball during an NFL football game between the Arizona Cardinals and the New York Giants at State Farm Stadium on September 17, 2023 in Glendale, Arizona. Photo by Michael Owens/Getty Images

Game-day update: Barkley is officially active for Sunday Night Football.

Game-day update: Jay Glazer says that Barkley is a game time decision, but likely to play.

Game day update: Barkley still isn’t guaranteed to play on Sunday night. He is trending in the right direction but will test the injury during pre-game warmups.

After missing the last two weeks of action with a high-ankle sprain, New York Giants running back Saquon Barkley has a shot at returning to the field this week when the Giants travel to face the Buffalo Bills on Sunday Night Football.

Barkley was a limited participant at practice all week, which is a good sign. The team listed him as questionable on the official injury report. However, given the nature of his injury, it’s no lock that he’ll suit up. Be sure to watch the news Sunday morning to get a sense of where things stand.

Betting and DFS implications for Week 6

I’m not sure that Barkley’s presence will have much impact on the Giants as 15-point underdogs. Tyrod Tayor is starting at quarterback this week, which certainly doesn’t help the situation, though I’m not sure how much it actually hurts either. The Giants offense would benefit from having Barkley back in action, and it would make that massive spread somewhat easier to cover.

As far as fantasy football lineups go, Barkley can be slotted into the second running back spot, if he plays. If he doesn’t, the team will use some combination of Eric Gray and Matt Breida. Gray had the edge in carries last week, 12 to nine. And both players had just one target and one catch. The week before that Breida had 14 carries. Still, I would shy away from either of those players if Barkley can’t go this week.