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Kyler Murray questionable for MNF Week 11 vs. 49ers

We break down the news that Kyler Murray is dealing with a hamstring injury. What it means for Week 11 and beyond.

Kyler Murray #1 of the Arizona Cardinals during warm up before the game against the Los Angeles Rams at SoFi Stadium on November 13, 2022 in Inglewood, California. Photo by Harry How/Getty Images

Saturday update: Murray is officially listed as questionable for Monday. Colt McCoy is not listed on the injury report, suggesting he’ll be the starting quarterback in the event Murray does not play.


Friday update: Murray will be a game-time decision, per John Weinfuss. Coach Kingsbury says the extra day due to the Monday night game will be helpful for Murray.

Friday update: After getting a limited practice in on Thursday, Murray was back at practice Friday, per Darren Urban. He has a chance to play this week, but hamstring injuries are fickle. Colt McCoy is also practicing and would likely be able to play if Murray sits.

Thursday update: Kyler Murray was practicing on Thursday, per John Weinfuss. Weinfuss also mentioned the quarterback was running quite a bit. This is a good sign as this is the first practice for the week due to the game being on Monday night.

Wednesday update: Head coach Kliff Kingsbury said Wednesday that Murray is day-to-day with a hamstring injury ahead of the Cardinals’ matchup with the 49ers.


The Arizona Cardinals are coming off a big win against the Los Angeles Rams. Quarterback Kyler Murray missed the game and is nursing a hamstring injury. He is a dual-threat quarterback, so his hamstring is essential for him to maximize his game. Backup quarterback Colt McCoy took over the offense and led the team to a win. Head coach Kliff Kingsbury said that Murray could sit again this week to further rest because he is 3-1 with McCoy starting, per ESPN.

Fantasy football implications for Week 11

McCoy missed part of last week’s game, but still went 26 for 37 passing for 238 yards and a touchdown. Even without Murray, DeAndre Hopkins saw 14 targets and had 98 yards receiving. The surprise was that Rondale Moore saw 13 targets and had nine receptions for 94 yards. This could also be because tight end Zach Ertz suffered an injury and will miss time.

If Murray is active, you can start Murray and Hopkins in your lineups. If it is McCoy again, start Hopkins and Moore.