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Tulane vs. Houston picks and best bets for Week 5 American Conference matchup

The Green Wave and Cougars meet in a Friday night battle on ESPN

Houston Cougars quarterback Clayton Tune looks for an open receiver during the first quarter against the Rice Owls at TDECU Stadium. Troy Taormina-USA TODAY Sports

It’s a matchup of two AAC teams that each have an unexpected loss so far this season when the Tulane Green Wave take on the Houston Cougars in the conference opener for both schools.

Both TU head coach Willie Fritz and UH’s Dana Holgorsen could use a victory to appease some fan bases that might be a bit on edge about their presence. But we’ll deep dive both teams here, and make a pick for the game!

SP+ Rankings

Tulane: 50 overall, 59 offense, 51 defense
Houston: 60 overall, 28 offense, 99 defense

Injury update


RB Cameron Carroll - questionable (leg)


RB Brandon Campbell - probable (ankle)


Against The Spread

Tulane: 3-1 ATS
Houston: 2-2 ATS


Tulane: Over 1-3
Houston: Over 4-0

Returning Talent from 247Sports

Tulane: 74 overall, 3 offense, 71 defense
Houston: 71 overall, 46 offense, 95 defense

Current lines at DraftKings Sportsbook

Spread: Houston -2.5
Total: 55
Moneyline: Houston -140, Tulane +120

Opening line: Houston -1
Opening total: 55


76 degrees, 6 MPH wind, 0% chance of rain

The Pick

Houston -2.5

While Clayton isn’t a world-beater, he’s simply got more weapons at his disposal than Michael Pratt does in this one. And where Houston’s defense lacks is in keeping up with elite speed, which is a spot that the Green Wave lack. UH has had fights on the sidelines, tons of terrible penalties, and looks extremely undisciplined overall. But at home, they still have enough horses to beat a scrappy-but-not-great team at home.

But if this was in New Orleans on a short week, we’d be going the other way of course.

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