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Fantasy football fallout from QB Trey Lance’s season-ending ankle injury

We discuss the fantasy football fallout of quarterback Trey Lance suffering an ankle injury on Sunday.

Trey Lance #5 of the San Francisco 49ers throws the ball during warmups before the game against the Seattle Seahawks at Levi’s Stadium on September 18, 2022 in Santa Clara, California. Photo by Thearon W. Henderson/Getty Images

Update: Lance’s injury is expected to require season-ending surgery, according to Adam Schefter. This means the 49ers will be rolling with Jimmy Garoppolo for the rest of the season. From a fantasy standpoint, you can see Garoppolo having about the same impact as Lance through the air. The quarterback change won’t impact San Francisco’s skill players much since this is basically reverting to last year’s offense. George Kittle will be back at some point as well, which should help. The real downside here is for fantasy managers who had Lance in the quarterback spot. Garoppolo is a solid addition off the waiver wire but there are other options with more upside mentioned already in this article.

San Francisco 49ers quarterback Trey Lance has been ruled out of the Week 2 game against the Seattle Seahawks. Jimmy Garoppolo has entered the game. Lance won the starting job in the offseason and was a top-10 fantasy quarterback for many analysts. He was carted off the field and was almost instantly ruled out for the game with an ankle injury.

Lance’s practice status will be very important as we head into next week. If it is an injury that will sideline him for the short term, you can likely use the waiver wire to find a serviceable backup to stream on a weekly basis. If it is a long-term injury, it depends on how you feel about Jimmy Garoppolo for the rest of the season. He’s shown some fantasy upside in the past with such strong YAC receivers, but he won’t give you a strong rushing floor like Lance would have.

If you do decide to go to the waiver wire, guys like Derek Carr, Tua Tagovalioa and Justin Fields could be long-term solutions if you are desperate. In the short-term, it will be based on matchup.