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Opening odds for each 2022 NFL Thursday Night Football matchup

With some solid matchups on tap, here’s a look at the lines for this season’s Thursday games.

NFL: Pittsburgh Steelers at Cleveland Browns Scott R. Galvin-USA TODAY Sports

With the full 2022 NFL schedule in hand, we can start looking ahead at some of the season’s matchups. We’ll have a full slate for Thursday night games this year. And breaking with the mid-week game’s less than stellar history, this year’s slate of contests has some pretty good matchups on tap.

Thursday night games get off to a great start with the Los Angeles Chargers at Kansas City Chiefs. Patrick Mahomes and Co. are still the favorites to win the AFC West, but it’s going to be a hard fought division.

Don’t sleep on the Saints-Cardinals game in Week 7 either. One team’s an underachiever and the other one’s an overachiever. It should be a good matchup. Another one to circle on your calendar is the late-season tilt between the Bills and Patriots, division rivals duking it out in primetime.

Here’s a list of opening odds for each Thursday night game this season.


Week 2: Chargers at Chiefs, 8:15 p.m. ET

Point spread: Chiefs -3
Point total: 52.5
Moneyline: Chiefs -160, Chargers +140

Week 3: Steelers at Browns, 8:15 p.m. ET

Point spread: TBD
Point total: TBD
Moneyline: TBD

Week 4: Dolphins at Bengals, 8:15 p.m. ET

Point spread: Bengals -4.5
Point total: N/A
Moneyline: Dolphins +165, Bengals -195

Week 5: Colts at Broncos, 8:15 p.m. ET

Point spread: Broncos -3
Point total: N/A
Moneyline: Colts +135, Broncos -155

Week 6: Commanders at Bears, 8:15 p.m. ET

Point spread: pk -110
Point total: N/A
Moneyline: Commanders -110, Bears -110

Week 7: Saints at Cardinals, 8:15 p.m. ET

Point spread: Cardinals -3
Point total: N/A
Moneyline: Saints +140, Cardinals -160

Week 8: Ravens at Bucs, 8:15 p.m. ET

Point spread: Bucs -3.5
Point total: N/A
Moneyline: Ravens +140, Bucs -160

Week 9: Eagles at Texans, 8:15 p.m. ET

Point spread: Eagles -4.5
Point total: N/A
Moneyline: Eagles -210, Texans +175

Week 10: Falcons at Panthers, 8:15 p.m. ET (Friday game)

Point spread: Panthers -3
Point total: N/A
Moneyline: Falcons +140, Panthers -160

Week 11: Titans at Packers, 8:15 p.m. ET

Point spread: Packers -4.5
Point total: N/A
Moneyline: Titans +170, Packers -200

Week 12: Patriots at Vikings, 8:20 p.m. ET (Thanksgiving on NBC)

Point spread: Vikings -2.5
Point total: not available
Moneyline: Vikings -140, Patriots +120

Week 13: Bills at Patriots, 8:15 p.m. ET

Point spread: Bills -3
Point total: N/A
Moneyline: Bills -145, Patriots +125

Week 14: Raiders at Rams, 8:15 p.m. ET

Point spread: Rams -4
Point total: N/A
Moneyline: Raiders +160, Rams -190

Week 15: 49ers vs. Seahawks, 8:15 p.m. ET

Point spread: 49ers -3
Point total: N/A
Moneyline: 49ers -160, Seahawks +140

Week 16: Jaguars at Jets, 8:15 p.m. ET

Point spread: Jets -2.5
Point total: N/A
Moneyline: Jaguars +115, Jets -135

Week 17: Cowboys at Titans, 8:15 p.m. ET

Point spread: Titans -1.5
Point total: N/A
Moneyline: Cowboys +110, Titans -130

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