Breaking down the Greensboro Region bracket in the NCAA Women’s Sweet 16

The Sweet 16 round of the Women’s NCAA Tournament will feature a pair of matchups from the Greensboro Region on Friday, March 25th. The first game will include the top-seeded South Carolina Gamecocks taking on the No. 5 seed North Carolina Tar Heels at 7:00 p.m. ET, followed by a matchup between the No. 3 Iowa State Cyclones and No. 10 Creighton Bluejays at approximately 9:30 p.m. ET.

Both games will be held at the Greensboro Coliseum in Greensboro, North Carolina, and can be seen on ESPN and ESPN2.

No. 1 South Carolina vs. No. 5 North Carolina (ESPN)

Point spread: South Carolina -10.5
Total: 117.5
Moneyline odds: South Carolina -510, North Carolina +375

South Carolina (31-2) has not had any issues to this point of the NCAA Tournament, blowing out No. 16 seed Howard 79-21 and the No. 8 Miami Hurricanes 49-33 to reach the Sweet 16. The Gamecocks have allowed opponents to shoot just 19% from the floor in the first two rounds. Aliyah Boston extended her double-double streak to 26 games heading into Friday night’s matchup.

North Carolina (25-6) took down the No. 12 seed Stephen F. Austin 79-66 in Round 1 and defeated the No. 4 seed Arizona Wildcats 63-45 in the second round. The Tar Heels rank No. 4 in opponent points per 100 possessions, and Kennedy Todd-Williams scored 34 points and grabbed 12 rebounds in the first two NCAA Tournament games combined.

No. 3 Iowa State vs. No. 10 Creighton (ESPN2)

Point spread: Iowa State -5.5
Total: 141.5
Moneyline odds: Iowa State -240, Creighton +195

Iowa State (28-6) pulled away late to beat the No. 14 seed UT Arlington 78-71 and had an easier time putting away the No. 6 seed Georgia Bulldogs 67-44 in Round 2. The Cyclones knocked down 16 3-pointers in their first two rounds, and Emily Ryan increased her assist average to 7.1 per game, which ranks third nationally.

Creighton (22-9) knocked off consecutive teams seeded higher than them with an 84-74 win over the No. 7 Colorado Buffaloes and a 64-62 victory to upset the No. 2 Iowa Hawkeyes. The Bluejays rank No. 1 in the country in assists per game, and Lauren Jensen scored 35 points with 10 rebounds in the first two NCAA Tournament rounds.

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL/IN/MI/NJ/PA/WV/WY), 1-800-NEXT STEP (AZ), 1-800-522-4700 (CO/NH), 888-789-7777/visit ccpg.org/chat (CT), 1-800-BETS OFF (IA), 1-877-770-STOP (7867) (LA), 877-8-HOPENY/text HOPENY (467369) (NY), visit OPGR.org (OR), call/text TN REDLINE 1-800-889-9789 (TN), or 1-888-532-3500 (VA).21+ (18+ NH/WY). Physically present in AZ/CO/CT/IL/IN/IA/LA/MI/NH/NJ/NY/OR/PA/TN/VA/WV/WY only. Eligibility restrictions apply. See draftkings.com/sportsbook for full terms and conditions.