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Mississippi State vs. Alabama odds heading into game week

Alabama will look to rebound from their first loss of the season as they welcome Mississippi State on Saturday.

TUSCALOOSA, ALABAMA - OCTOBER 08: Bryce Young #9 of the Alabama Crimson Tide leads the team onto the field during pregame warmups prior to facing the Texas A&M Aggies at Bryant-Denny Stadium on October 08, 2022 in Tuscaloosa, Alabama. Photo by Kevin C. Cox/Getty Images

Two teams motivated to rebound from losses go head-to-head as the No. 16 Mississippi State Bulldogs face the No. 3 Alabama Crimson Tide in Tuscaloosa, AL on Saturday, October 22 at 7:00 p.m. ET. The game is scheduled to air on ESPN.

Mississippi State (5-2, 2-2 SEC) suffered its second loss of the season after falling 27-17 to Kentucky. The Bulldogs had no answer for Chris Rodriguez Jr., who finished with 196 rushing yards and two fourth-quarter scores in the winning effort. The loss means that Mississippi State’s three-game losing streak officially came to end. The bright spot, however, is that the Bulldogs should still expect to remain ranked as they prepare for a bout against the Crimson Tide on Saturday.

Alabama (6-1, 3-1 SEC) saw its 15-game winning streak against Tennessee snapped in a 52-49 loss on Saturday night, marking the Crimson Tide’s first loss of the season. In a back-and-forth high-scoring affair between SEC heavyweights, Chase McGrath made a 40-yard field goal as time expired to give No. 6 Tennessee a long-awaited victory. Bryce Young threw for 455 yards and two touchdowns as Alabama looks to rebound against the Rebels on Saturday night.

Mississippi State vs. Alabama opening odds

Spread: Alabama -22.5
Total: 60.5