Auburn (3-3, 1-2 SEC) will look to avoid a third consecutive loss and is coming off a 42-10 defeat against the Georgia Bulldogs on the road. Robby Ashford completed 13-of-38 passes for 165 yards with a touchdown and lost a fumble, filling in for TJ Finley.
Ole Miss (6-0, 2-0 SEC) has a great chance to remain undefeated, and the Rebels totaled 591 total yards of offense in a 52-28 win over the Vanderbilt Commodores. Jaxson Dart completed 25-of-32 passes for 448 yards with three touchdowns and two interceptions, and he connected with Jonathan Mingo, who caught nine passes for 247 yards and two scores.
Ole Miss is a 14.5-point favorite on DraftKings Sportsbook with -700 moneyline odds, making Auburn a +510 underdog. The over/under is set at 55.5.