Who has the best worst odds to reach Final Four out of the Midwest region after first round

The 2021 NCAA Tournament is in full swing as the second round is set to kick off Sunday, March 21st. The Midwest region of the bracket is loaded with talented programs that could go the distance, but we saw a couple notable upsets that have shaken things up. No. 12 Oregon State and No. 11 Syracuse upended a higher seed in round one, and both cruised to victory in convincing fashion.

Let’s take a look at the odds of some of its top contenders at DraftKings Sportsbook as we enter the second round of March Madness.

Illinois had no trouble with Drexel and remains the clear favorite improving from +150 to +125. However, with the top four seeds all advancing, they still face some tough challenges. The Illini will be cheering on the underdogs in their region, but the Illini are a No. 1 for a reason. Oregon State had the biggest move, improving from +6000 to +1000.

Here are the odds for each remaining team in the Midwest region to make it to the Final Four entering the second round of the tournament. Feel free to compare them to each team’s odds entering the tournament.

No. 1 Illinois +125
No. 2 Houston +250
No. 4 Oklahoma State +500
No. 3 West Virginia +500
No. 8 Loyola Chicago +900
No. 11 Syracuse +900
No. 12 Oregon State +1000

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