clock menu more-arrow no yes mobile

Filed under:

Full list of opening odds for second round of 2021 NCAA Tournament

Here’s the complete list of odds for the second round of the 2021 NCAA Tournament coming to you from four arenas in Indiana.

Oral Roberts Golden Eagles link arms and bow their heads following their win over Ohio State Buckeyes in overtime during the first round of the 2021 NCAA Tournament on Friday, March 19, 2021, at Mackey Arena in West Lafayette, Ind. IndyStar-USA TODAY Sports

The NCAA Tournament is underway and matchups are quickly being settled in the Round of 32. The first round has already seen a huge upset, with No. 15 Oral Roberts knocking off No. 2 Ohio State. It marks the ninth time in tournament history a No. 15 has beaten a No. 2. Apologies to those of you who had the Buckeyes making a run in your bracket.

Second round matchups bring with them a new set of odds. The first round does not wrap until late Saturday night, but we already have lines for the confirmed second round matchups. The round of 32 tips at noon on Sunday. In the meantime, here is where odds are opening for all the second round games in the 2021 NCAA Tournament from DraftKings Sportsbook. It’s worth noting, that if Rutgers advances, their second round line will not be available for New Jersey customers due to New Jersey regulations. The line is available in other states where DraftKings Sportsbook operates.

South region

No. 1 Baylor vs. No. 9 Wisconsin
Point spread: Baylor -6.5
Total: 137
Moneyline: Baylor -286, Wisconsin +235

No. 3 Arkansas vs. No. 6 Texas Tech
Point spread: Texas Tech -0.5
Total: 140.5
Moneyline: Arkansas -109, Texas Tech -109

No. 5 Villanova vs. No. 13 North Texas
Point spread: Villanova -6.5
Total: 126.5
Moneyline: Villanova -295, North Texas +235

No. 7 Florida vs. No. 15 Oral Roberts
Point spread: Florida -7.5
Total: 148.5
Moneyline: Florida -345, Oral Roberts +280

Midwest region

No. 1 Illinois vs. No. 8 Loyola Chicago
Point spread: Illinois -7
Total: 132.5
Moneyline: Illinois -315, Loyola +255

No. 2 Houston vs. No. 10 Rutgers
Point spread: Houston -9
Total: 132
Moneyline: Houston -455, Rutgers +360

No. 3 West Virginia vs. No. 11 Syracuse
Point spread: West Virginia -3.5
Total: 147
Moneyline: West Virginia -167, Syracuse +140

No. 4 Oklahoma State vs. No. 12 Oregon State
Point spread: Oklahoma State -6
Total: 142
Moneyline: Oklahoma State -265, Oregon State +215

West region

No. 8 Oklahoma vs. No. 1 Gonzaga
Point spread: Gonzaga -15
Total: 154
Moneyline: Gonzaga -1430, Oklahoma +850

No. 7 Oregon vs. No. 2 Iowa
Point spread: Iowa -4
Total: 145.5
Moneyline: Iowa -182, Oregon +155

No. 6 USC vs. No. 3 Kansas
Point spread: Kansas -0.5
Total: 135
Moneyline: Kansas -109, USC -109

No. 13 Ohio vs. No. 5 Creighton
Point spread: Creighton -5
Total: 149.5
Moneyline: Creighton -220, Ohio _180

East region

No. 8 LSU vs. No. 1 Michigan
Point spread: Michigan -5
Total: 148
Moneyline: Michigan -220, LSU +180

No. 10 Maryland vs. No. 2 Alabama
Point spread: Alabama -5
Total: 137
Moneyline: Alabama -220, Maryland +180

No. 5 Colorado vs. No. 4 Florida State
Point spread: FSU -1.5
Total: 140
Moneyline: FSU -124, Colorado +104

No. 14 Abilene-Christian vs. No. 11 UCLA
Point spread: UCLA -5
Total: 135.5
Moneyline: UCLA -210, Abilene Christian +175

If you or someone you know has a gambling problem, crisis counseling and referral services can be accessed by calling 1-800-GAMBLER (1-800-426-2537) (IL). Gambling problem? Call 1-800-GAMBLER (NJ/WV/PA/MI), 1-800-9-WITH-IT (IN), 1-800-522-4700 (NH/CO), 1-800-BETS OFF (IA), 1-888-532-3500 (VA) or call/text TN REDLINE 1-800-889-9789 (TN). 21+ (18+ NH). CO/IL/IN/IA/NH/NJ/PA/TN/VA/WV/MI only. Eligibility restrictions apply. See for full terms and conditions.