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No. 12 Ole Miss vs. LSU picks and best bets for Week 8

The LSU Tigers and Ole Miss Rebels meet in the first game since the announcement of 2021 being Ed Orgeron’s final season in Baton Rouge.

Florida v LSU Photo by Jonathan Bachman/Getty Images

The LSU Tigers will begin a bit of an awkward stretch run of their season with Ed Orgeron leading the charge even though he will no longer be the head coach in 2022. This was obvious given how this season began, but now it’s official that one of the best jobs in college football will be available. LSU will play spoiler the rest of the season, and they will head on the road to see a much-improved Ole Miss Rebels team that could be without starting quarterback Matt Corral, who is among the favorites to win the Heisman Trophy.

Here’s all the data you’ll want, and a pick for the game!

SP+ Rankings

Ole Miss: 20 overall, 5 offense, 66 defense
LSU: 45 overall, 17 offense, 82 defense

Injury update

Ole Miss

QB Matt Corral - Doubtful (undisclosed)
WR Braylon Sanders - Questionable (lower body)


DB Major Burns - Questionable (undisclosed)
DT Joseph Evans - Questionable (undisclosed)
WR Deion Smith - Questionable (undisclosed)
WR Devonta Lee - Questionable (undisclosed)
T Austin Deculus - Questionable (shoulder)
WR Brian Thomas Jr. - Questionable (undisclosed)
RB Armoni Goodwin - Questionable (undisclosed)


Against The Spread

Ole Miss: 3-2-1 ATS
LSU: 3-4 ATS


Ole Miss: Over 3-3
LSU: Over 4-3

Returning/Overall Talent from 247Sports

Ole Miss: 22 overall, 20 offense, 33 defense
LSU: 7 overall, 13 offense, 4 defense

Current lines at DraftKings Sportsbook

Spread: Ole Miss -7.5
Total: 77
Moneyline: Ole Miss -335, LSU +260

Opening line: Ole Miss -12
Opening total: 75.5


78 degrees, 7 MPH wind, 11% chance of rain

The Pick

Ole Miss -7.5

With or without Matt Corral, Ole Miss has plenty of value as long as the spread stays under 10 points. Lane Kiffin will set up any quarterback who lines up under center for success, and it will be difficult to see how LSU can consistently get stops. The Tigers allowed 42 points in each of their last two games against the Kentucky Wildcats and Florida Gators. When you combine a lack of defense with an awkward situation at the top of the program, we’re riding with the Rebels on Saturday afternoon.

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