Carolina has won four straight games with Kyle Allen under center, and will look to take down the undefeated 49ers after their bye week. Allen has been excellent, posting a 7.21 adjusted net yards per pass attempt, eighth-best in the NFL. The Panthers have been even better on defense, allowing just 4.1 adjusted net yards per pass attempt, third-best in the league. Carolina enters this game having scored 34 or more points in three of their past four games, and four of six overall.

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The 49ers are 6-0, and have a +92 point differential, behind only the Patriots. A huge part of that success has been their defense, which has come out of nowhere to be the second-rated NFL defense in terms of Football Outsiders DVOA. First round pick Nick Bosa has 21 pressures, tied for 11th in the NFL among defensive-linemen, according to Sports Info Solutions. The Niners have also run the ball effectively, averaging 172.7 yards per game (second in the league), and a steady 4.4 yards per carry (12th). This is of particular note in this matchup given that the Panthers are the 30th ranked rush defense by DVOA. Jimmy Garoppolo is averaging 7.9 yards per pass attempt, good for ninth in the NFL.

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Panthers at 49ers

Betting Odds

Point Spread: Panthers +5.5
Total Points: 41.5
Money Line: 49ers -245; Panthers +200

Records

Overall 2019: Panthers 4-2; 49ers 6-0
ATS 2019: Panthers 4-2; 49ers 4-2
O/U 2019: Panthers 4-2; 49ers 1-5

Notable Prop Bets

Panthers Total Touchdowns - Over 1.5 -186, Under 1.5 +140
49ers Total Points - Over 23.5 -106, Under 23.5 -122
Total Game Touchdowns - Over 4.5 -105, Under 4.5 -130
First Team to Score - Panthers +120, 49ers -165

Betting Trends

• The Panthers have won each of their last six October games as underdogs.
• The 49ers have failed to cover the spread in each of their last nine Sunday games as home favorites.
• Each of the 49ers’ last four games have gone UNDER the total points line.

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